Attachment 1




Hanford Occupational Health Foundation
MEDICAL DENTAL BLDG.		  RICHLAND WASH.99382


March 11, 1966


U.S. Atomic Energy Commission
Richland Operations Office
Richland, Washington

Attention:  A.M. Waggoner, Assistant Manager for Administration

Subject:  Proposed Promethium and Plutonium Studies

Gentlemen:

As part of the Whole Body Counting - Metabolic Studies of
Radioisotopes in Humans studies, Battelle Northwest personnel
propose to perform , ingestion, injection, and inhalation studies
involving Promethium 144 and Plutonium 237.  This program will
involve the use of paid volunteers, and possibly employees, who
will receive controlled doses of Pm144 and Pu237.  Estimated doses
will be in the range of 0.1 to 0.15 roentgens.  Dr. Dave Bruner of
the AEC Division of Biology and Medicine concurs in our belief that
such studies may prove extremely useful.

Since these experiments will provide valuable data for use in
possible treatment of radiation and contamination victims as well
as basic research information, the Hanford Occupational Health
Foundation is quite anxious to participate in the program.

Participation in such a program, however, raises several legal
questions.  Article XVI - Litigation and Claims, of Contract AT
(45-1)-1837 provides for reimbursement to the Foundation of costs
incurred in the settlement or defense of a claim if not otherwise
covered by insurance.  The Foundation Liability insurance does not
provide protection against a claim which might arise as a result of
participation in the subject program.

Since this program is a part of an approved Commission program,
would the Foundation be protected under the provisions of Article
XVI, insofar as reimbursement of costs is concerned?

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The Foundation would be involved in the examination of the
volunteers, administration of the radioisotopes, interpretation of
results, and payment of the volunteers.  It is felt that a document
executed by the volunteers, possibly an authorization or consent
form, would be desirable and appropriate.  Guidance as to consent
and format of such a document from the Commission Legal offices is
requested.

Hanford Occupational Health Foundation


U.S. Atomic Energy Commission
Page Two
March 11, 1966


A third problem involves licensing.  It is our understanding that
AEC approved programs involving the use of radioisotopes which are
conducted in Commission owned facilities do not require a license. 
 It is possible that some of the work will be performed in Kadlec
Hospital.  If so, would this require a license?  Would a license be
required for work in our Richland headquarters in the Kadlec
Medical Dental Building?

Your reply to the above questions and request at the earliest
convenient time will be appreciated.  If you have any questions or
desire additional information, please feel free to contact me.

Very truly yours,

W.D. Norwood, M.D.
Medical Director

MDN/jg

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