BIBLIOGRAPHY ON NASA-SPONSORED RADIATION RESEARCH INVOLVING HUMAN SUBJECTS Report on a literature search R. Dutcher, R. W. Dunning, and W. Schimmerling On January 24, 1994, Dr. Joan Vemikos, Director of the Life and Biomedical Sciences and Applications Division, instructed Dr. Walter Schimmerling, Program Scientist for the NASA Space Radiation Health Program, to initiate a literature search of all publications relevant to possible radiation exposure of human subjects, that has been reported as a result of research sponsored by NASA. This literature search was intended to support the activities of the panel chaired by Dr. Donald E. Robbins, charged by the NASA Administrator, Mr. Goldin, to search all records relevant to radiation exposures of human subjects in the course of research sponsored by NASA. The results of this literature search are summarized in Table I. The primary search was done TABLE I Database: RECON #1 Keywords: Radiation effects, radiation dosage, radiation hazards, radiation injuries, radiation sickness, radiation therapy, nuclear radiation, nuclear medicine, radiobiology; combined with human beings, females, males, human body, humans; also combined physiology effect, biological effects, and human behavior with some of the above terms No. of Citations: 830 No of Leads: 232 Sel Pubs: 25 Database: RECON #2 Keywords: Nuclear medicine, radiobiology, radioactive isotopes, radiation absorption; against human, biological, and physiological-like terms No. of Citations: 447 No of Leads: 65 Sel Pubs: 12 Database: RECON #3 Keywords: Radiation (which has many subterms under it), radiation injuries, nuclear medicine; against contracts and grants let by NASA (this part of the database begins in 1972) No. of Citations: 406 No of Leads: 27 Sel Pubs: 0 Database: Nuclear Science Abstracts, NTIS Medicine databases Keywords: Backup searches. Mostly overlap with records supplied by RECON. No. of Citations: 30 No of Leads: 10 Sel Pubs: 1 Database: NACA Keywords: Checked printed indexes for NACA (predecessor to NASA) covering the period from the 1940's to 1961. No. of Citations: 34 No of Leads: 0 Sel Pubs: 0 Database: Review articles, books Keywords: Scanned 25 review articles and 15 books for leads. No. of Citations: 30 No of Leads: 50 Sel Pubs: 9 Database: RECON #4 Keywords: Numerous specific terms: Photon absorptiometry; neuron, neutron sources, neutron activation analysis, neutron irradiation, neutron beams, etc; x-rays, x-ray analysis, etc.; tomography, computer aided tomography; radiography; irradiation, ion irradiation, ion beams, particle beams, proton beams, etc.; isotopic labeling, positrons, PET; all of above combined with various life science terms; also selected names of investigators already identified No. of Citations: 630 No of Leads: 60 Sel Pubs: 39 Database: MANUAL SEARCHING Keywords: Manual scanning of GWU/USUHS bibliographic database; manual scanning of bedrest studies bibliography; reading retrieved papers and pursuing references cited in them, checking various other sources including additional reviews and books, etc. No. of Citations: --- No of Leads: 620 Sel Pubs: 103 TOTAL No. of Citations: 2407 TOTAL No of Leads: 1064 TOTAL Sel Pubs: 189 1 on NASA's RECON in-house database, whose coverage begins around 1962. A total of 4 searches of the RECON database were conducted; the last three were iterations based on the results of the first search, on information obtained from the other data bases, and on information obtained from the text and the references of publications as they became available. A total of 2407 citation were found in the initial searches, using the broadest possible, criteria in order to look for all references that could possibly be relevant. A total of 1064 citations, resulting from the initial searches, were identified as "leads". Leads were pursued by examining a copy of the paper when possible, by examining the abstract, grant/contract number, or whatever other information was available from the search, or by doing additional searching on the investigators' names. Through this process, the leads were reduced to 189 publications judged to be relevant. The results of the literature search consist of: (1) this summary description; (2) a summary of the 189 publications judged relevant, indicating the author(s), full reference of the publication, and type of radiation, and (3) a limited number of complete sets of copies of the relevant publications, team headed by Dr. Robbins. In addition, the summary of the relevant publications is available as a computer-readable file, for use as a spreadsheet. In order to assist in the evaluation of this bibliography, the results of the literature search have been classified in Tables II- X by research group and research type, as follows: TABLE RESEARCH GROUP/TYPE II U.Washington/Battelle Northwest Labs -- W.B. Nelp, T.K. Lewellen, H.E. Palmer, e.g., neutron irradiation, 37Ar measured in breath (10 publications) III Oak Ridge Laboratory group -- C.C. Lushbaugh; co-funding with AEC; data analyzed for patients irradiated for therapeutic purposes (8 publications) IV Therapeutic irradiation of a patient with a skin condition -- H. Aceto (1 publication) V Irradiation of pancreatic cancer patients with neutrons - - Cleveland Clinic/Lewis Research Center (1 publication) VI Neutron Activation Analysis -- A. LeBlanc, P. Johnson (2 publications) VII Observations and investigations of visual light flash phenomena -- two main groups of investigations conducted at several facilities (21 publications) VIII Astronaut studies, in space and on the ground, including radiation exposure in space, tracer and scan studies, indirect studies such as assessment of induced radionuclides and chromosomes in blood samples (42 publications) IX Scans (not astronauts), e.g., for bone mineral and skeletal changes -- x-ray densitometry, photon absorptiometry, etc. (53 publications) X Use of tracers (not astronauts); many were bedrest studies (51 publications) While it is never possible to claim that a literature search has exhausted all possibilities, the authors of this report feel confident that they have exercised all due diligence in their examination of the published literature and that the present data base is as full an accounting as can be achieved with the means at our disposal. 2 NASA RADIATION CITATIONS TABLE II. U. Washington/Battelle Northwest -- n activation of Ar No.: 1 Authors: Lewellen, T.K.; Chestnut, C.H., III; Nelp, W.B.; Palmer, H.E.; Murano, R.; Hinn, G.M. Report Title: Preliminary observation on excretion of 37Ar from man following whole-body neutron activation - an indicator of total-body calcium. Citation: Journal of Nuclear Medicine 16: 672-675, 1975 Radiation Type: n No.: 2 Authors: Lewellen, T.K.; Nelp, W.B. Report Title: Total Body Calcium Analysis. Citation: Annual report, NASA Contract NAS 9-13029, November 1, 1972 to October 1, 1974, 46 p., 1974. (NASA-CR- 141573) Radiation Type: n No.: 3 Authors: Lewellen, T.K.; Nelp, W.B. Report Title: Total Body Calcium Analysis Using the 40Ca(n, alpha)37Ar reaction. Citation: Final Technical Report, 10/1/76-12/1/77, NAS9- 13029, 31 P., 1978. (NASA-CR-151675) Radiation Type: N No.: 4 Authors: Lewellen, T.K.; Nelp, W.B.; Palmer, H.E.; Murano, R.; Hinn, G.M. Report Title: A system for measuring total body calcium in man using the 40Ca(n,alpha)37Ar reaction. Citation: Physics in Medicine And Biology 24(1): 124-135, 1979. Radiation Type: n No.: 5 Authors: Lewellen, T.K.; Nelp, W.B.; Palmer, H.E. Report Title: Argon-37 excretion in humans following total-body neutron activation. Citation: Transactions of the American Nuclear Society 18: 97-98, 1974. Radiation Type: n No.: 6 Authors: Palmer, H.E. Report Title: Continued Investigation of Kinetic Aspects of Bone Mineral Metabolism. Citation: Final Report, NASA Contract NAS 9-13235, February 1, 1973-February 28, 1974 to NASA Lyndon B. Johnson Space Center, 29 p., February 26, 1974. (NASA-CR- 141607) Radiation Type: n No.: 7 Authors: Palmer, H.E. Report Title: Investigate Methods for Measuring Muscle and Bone Mass Changes in Astronauts and Animals Which Occur During Space Flight. Citation: Final Report, NASA Contract NAS9-14248, December 1, 1976-August 31, 1977 to NASA Lyndon B. Johnson Space Center, 23 p., August 31, 1977. (NASA-CR- 151518) Radiation Type: n Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE II. U. Washington/Battelle Northwest -- n activation of Ar No.: 8 Authors: Palmer, H.E. Report Title: Regional Measurement of Body Nitrogen. Citation: Final Report, NASA Contract NAS 9-14248, February 1, 1976-October 31, 1976 to NASA Lyndon B. Johnson Space Center, 21 p., October 31, 1976. (NASA-CR- 151200) Radiation Type: n No.: 9 Authors: Palmer, H.E. Report Title: Total Body Nitrogen Analysis. Citation: Final Report, NASA Contract NAS 9-14248, February 1, 1975-October 31, 1975 to NASA Lyndon B. Johnson Space Center, 17 p., November 28, 1975. (NASA-CR- 144653) Radiation Type: n No.: 10 Authors: Palmer, H.E.; Rieksts, G.A. Report Title: Determination of muscle mass changes in legs from 40k measurements. Citation: Aviation, Space and Environmental Medicine 50: 961- 963, 1979. Radiation Type: n Page 2 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE III. Oak Ridge National Laboratory -- whole body radiotherapy No.: 1 Authors: Lushbaugh, C.C. Report Title: Chapter 10: Human radiation tolerance. Citation: Space Radiation Biology and Related Topics (Tobias, C.A.; Todd, P., Eds.). New York: Academic Press, 1974, p. 475-522. Radiation Type: All No.: 2 Authors: Lushbaugh, C.C. Report Title: Predicted levels of human radiation tolerance extrapolated from clinical studies of radiation effects. Citation: Proceedings of the National Symposium on Natural and Manmade Radiation in Space (Warman, E.A., Ed.). Washington, DC: National Aeronautics and Space Administration, 1972, p. 398-415. (NASA TM X-2440) Radiation Type: All No.: 3 Authors: Lushbaugh, C.C., Hofstra, R.; Roth, R.E.; Andrews, G.A. Report Title: Radiosensitivity in man: A study based on therapeutic and accidental exposure. Citation: Oak Ridge Institute of Nuclear Studies. Medical Division-Research Report, Year ending December 31, 1964, p. 128-131, 1964. (ORINS-49) Radiation Type: x-ray gamma No.: 4 Authors: Lushbaugh, C.C.; Comas, F.; Saenger, E.L.; Jacobs, M.; Hofstra, R.; Andrews, G.A. Report Title: Radiosensitivity of man by extrapolation from studies of total-body irradiation of patients (Abstract). Citation: Radiation Research 27: 487-488, 1966. Radiation Type: x-ray gamma No.: 5 Authors: Lushbaugh, C.C.; Comas, F.; Hofstra, R. Report Title: Clinical studies of radiation effects in man. A preliminary report of a retrospective search for dose-relationships in the prodromal syndrome. Citation: Radiation Research Supplement 7: 398-412, 1967. Radiation Type: All No.: 6 Authors: Ricks, R.C.; Lushbaugh, C.C. Report Title: Studies Relative to the Radiosensitivity of Man: Based on Retrospective Evaluations of Therapeutic and Accidental Total-Body Irradiation. Citation: Final Report, 226 p., 1975. (NASA-CR-14439) Radiation Type: x-ray gamma Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE III. Oak Ridge National Laboratory -- whole body radiotherapy No.: 7 Authors: Ricks, R.C.; Lushbaugh, C.C.; McDow, E.; Frome, E. Report Title: Pulmonary-impedance power spectral analysis: A facile means of detecting radiation-induced gastrointestinal distress and performance decrement in man. Citation: Proceedings of the National Symposium on Natural and Manmade Radiation in Space (Warman, E.A., Ed.). Washington, DC: National Aeronautics and Space Administration, 1972, p.238-248. (NASA TM X-2440) Radiation Type: Y No.: 8 Authors: Yuhas, J.M.; Stokes, T.R.; Lushbaugh, C.C.; Report Title: Multifactorial analysis of human blood cell responses to clinical total body irradiation. Citation: Proceedings of the National Symposium on Natural and Manmade Radiation in Space (Warman, E.A., Ed.). Washington, DC: National Aeronautics and Space Administration, 1972, p.233-237. (NASA TM X-2440) Radiation Type: All Page 2 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IV. Space Radiation Effects Laboratory - Radiotherapy of patient with skin condition No.: 1 Authors: Angio, G.J.; Aceto, H.; Nisce, L.Z.; Kim, J.H.; Jolly, R.; Buckle, D.; Holt, J.G.; Report Title: Preclinical observations after extended Bragg peak helium ion irradiation. Citation: Cancer 34: 6-11, 1974. Radiation Type: alpha e- Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE V. Cleveland Clinic/Lewis Research Center - Radiotherapy of pancreatic cancer patients No.: 1 Authors: Gahbauer, R.; Koh, K.Y.; Rodriguez-Antunez, A.; Jelden, G.L.; Turco, R.F.; Horton, J.; Bukowski, R.; Reimer, R.; Blue, J.; Robert, W.; Leonard, R. Report Title: Preliminary Results of Fast Neutron Treatments in Carcinoma of the Pancreas Citation: Report prepared for the National Pancreatic Project, New Orleans, Louisiana, April 18, 1980, 4 p., 1980 (NASA-TM-81516) Radiation Type: n Page 2 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VI. LeBlanc et al., In activation analysis No.: 1 Authors: LeBlanc, A.D.; Evans, H.J.; Johnson, P.C.; Loeffler, S.H. Report Title: Partial body activation analysis using a Californium-252 source. Citation: Proceedings of the Fourth International Conference on Bone Measurement, University of Toronto, Ontario, Canada, June 1-3, 1978, U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, P. 379-385, 1980 Radiation Type: n No.: 2 Authors: Suki, W.; Johnson, P.C.; Leblanc, A.; Evans, H.J.; Report Title: Analysis of Body Calcium (Regional Changes in Body Calcium by In Vivo Neutron Activation Analysis). Citation: Final Report, Contract NAS 9-13737, 108 p., 1981. (NASA-CR-161027) Radiation Type: n Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VII. Study of visual light flash phenomena -- various institutions and facilities No.: 1 Authors: Budinger, T.F.; Bichsel, H.; Tobias, C.A. Report Title: Visual phenomena noted by human subjects on exposure to neutrons of energies less than 25 million electron Citation: Science 172(3985): 868-870, 1971. Radiation Type: n No.: 2 Authors: Budinger, T.F.; Lyman, J.T.; Tobias, C.A. Report Title: Visual perception of accelerated nitrogen nuclei interacting with the human retina. Citation: Nature 239(5396): 209-211, 1972. Radiation Type: Heavy ion (N) No.: 3 Authors: Budinger, T.F.; Tobias, C.A.; Huesman, R.H.; Upham, F.T.; Wieskamp, T.F.; Hoffman, R.A. Report Title: Apollo-Soyuz light-flash observations. Citation: Life Sciences And Space Research 15: 141-146, 1977 Radiation Type: Space No.: 4 Authors: Budinger, T.F.; Tobias, C.A.; Huesman, R.H.; Upham, F.T.; Wieskamp, T.F.; Schott, J.-U.; Schopper, E. Report Title: Chapter 12, Light flash observations. Experiment MA-106 Citation: Apollo-Soyuz Test Project Summary Science Report, Volume 1. Washington, D.C.: National Aeronautics and Space Administration, p. 193-209, 1977. Radiation Type: Space No.: 5 Authors: Chapman, P.K.; Pinsky, L.S.; Benson, R.E.; Budinger, T.F. Report Title: Observations of cosmic-ray induced phosphenes on Apollo 14. Citation: Proceedings of the National Symposium on Natural and Manmade Radiation in Space (Warman, E.A., Ed.). Washington, DC: National Aeronautics and Space Administration, 1972, p. 1002-1006. (NASA TM X- 2440) Radiation Type: Space No.: 6 Authors: Hoffman, R.A.; Pinsky, L.S.; Osborne, W.Z.; Bailey, J.V. Report Title: Visual light flash observations on Skylab 4. Chapter 14. Citation: Biomedical Results from Skylab (Johnson, R.S.; Dietlein, L.F., eds). Washington, D.C.: NASA, p. 127-130, 1977. (NASA SP-377) Radiation Type: Space No.: 7 Authors: Liwshit, M. Report Title: The Origin of Light Flashes Observed by Apollo Astronauts. Citation: Technical Memorandum prepared for Bellcom, Inc., Washington, D.C., 1971. (NASA-TM-71-2015-5) Radiation Type: Space Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VII. Study of visual light flash phenomena -- various institutions and facilities No.: 8 Authors: McNulty, P.J. Report Title: Light flashes produced in the human eye by extremely relativistic muons. Citation: Nature 234: 110, 1971 Radiation Type: mu No.: 9 Authors: McNulty, P.J.; Pease, V.P.; Bond, V.P. Report Title: Visual sensations induced by Cerenkov radiation. Citation: Science 189: 453-454, 1975. Radiation Type: pi - mu+ No.: 10 Authors: McNulty, P.J.; Pease, V.P.; Bond, V.P. Report Title: Visual phenomena induced by relativistic carbon ions with and without Cerenkov radiation. Citation: Science 201: 3341-343, 1978. Radiation Type: Heavy ion C No.: 11 Authors: McNulty, P.J.; Pease, V.P.; Bond, V.P. Report Title: Visual sensations induced by relativistic pions. Citation: Radiation Research 66: 519-530, 1976 Radiation Type: pi No.: 12 Authors: McNulty, P.J.; Pease, V.P.; Bond, V.P. Report Title: Role of Cerenkov radiation in the eye-flashes observed by Apollo astronauts. Citation: Life Sciences and Space Research 14: 205-217, 1976. Radiation Type: Space No.: 13 Authors: McNulty, P.J.; Pease, V.P.; Pinsky, L.S.; Bond, V.P.; Schimmerling, W.; Vosburgh, K.G. Report Title: Visual sensations induced by relativistic nitrogen nuclei. Citation: Science 178: 160-162, 1972. Radiation Type: Heavy ion N No.: 14 Authors: McNulty, P.J.; Filz, R.C.; Rothwell, P.L. Report Title: Role of nuclear stars in the light flashes observed on Skylab 4. Citation: Life Science and Space Research 15: 129-134, 1977 Radiation Type: Space No.: 15 Authors: McNulty, P.J.; Pease, V.P. Report Title: Light Flash Phenomena Induced by HZE Particles. Citation: Final Report, NASA Grant NSG 9059, March 31, 1980, 51 p. (NASA-CR-163011) Radiation Type: Heavy Ions (C, Ne, N) No.: 16 Authors: Osborne, W.Z.; Pinsky, L.S.; Bailey, J.V. Report Title: ALFMED Experiment. In: Chapter 2, Apollo Light Flash Investigations. Citation: Biomedical Results of Apollo (Johnston, R.S.; Dietlein, L.F.; Berry, C.A., eds.). Washington, D.C.: NASA, p. 361-365, 1975. (NASA SP-368) Radiation Type: Space Page 2 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VII. Study of visual light flash phenomena -- various institutions and facilities No.: 17 Authors: Pinsky, L.S.; Osborne, W.Z.; Bailey, J.V.; Benson, R.E.; Thompson, L.F. Report Title: Light flashes observed by astronauts on Apollo 11 through Apollo 17. Citation: Science 183: 957-959, 1974. Radiation Type: Space No.: 18 Authors: Tobias, C.A.; Budinger, T.F.; Lyman, J.T.; Report Title: Biological effects due to single accelerated heavy particles and the problems of nervous system exposure in space. Citation: Life Sciences and Space Research 11: 233-245, 1973 Radiation Type: Heavy ions, N, O No.: 19 Authors: Tobias, C.A.; Budinger, T.F.; Leith, J.T.; Mamoon, A.; Chapman, P. Report Title: Visual phenomena induced by cosmic rays and accelerated particles. Citation: Special Biophysical Problems in Aerospace Medicine, AGARD Conference Proceedings No. 95, Part III (Pfister, A.M., ed.). London: Harford House, p. C6-1 - C6-12, 1972. (AGARD-CP-95-Part III) Radiation Type: n, pi, alpha, Space No.: 20 Authors: Tobias, C.A.; Budinger, T.F.; Lyman, J.T. Report Title: Radiation-induced light flashes observed by human subjects in fast neutron, X-ray and positive pion beams. Citation: Nature 230(5296): 596-598, 1971. Radiation Type: n, X-ray, pi No.: 21 Authors: Tobias, C.A.; Budinger, T.F.; Lyman, J.T. Report Title: Human visual response to nuclear particle exposures. Citation: Proceedings of the National Symposium on Natural and Manmade Radiation in Space (Warman, E.A., Ed.). Washington, DC: National Aeronautics and Space Administration, 1972, p. 416-422. (NASA TM X-2440) Radiation Type: * Page 3 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VIII. Astronaut studies including space radiation exposure, tracer and scan studies, and assessment of activation of blood samples No.: 1 Authors: Bailey, J.V. Report Title: In-flight radiation detection. Chapter 5. Citation: The Apollo-Soyuz Test Project Medical Report (Nicogossian, A.E., comp.). Washington, D.C.: NASA, p. 29-31, 1977. (NASA SP-411) Radiation Type: all No.: 2 Authors: Bailey, J.V.; Hoffman, R.A.; English, R.A. Report Title: Radiological protection and medical dosimetry for the Skylab crewmen. Chapter 9. Citation: Biomedical Results from Skylab (Johnston, R.S.; Dietlein, L.F., eds.). Washington, D.C.: NASA, p. 64-69, 1977. (NASA SP-377). Radiation Type: all No.: 3 Authors: Bender, M.A.; Gooch, P.C.; Kondo, S. Report Title: The Gemini-3 S-4 spaceflight-radiation interaction experiment. Citation: Radiation Research 31: 91-111, 1967. Radiation Type: beta No.: 4 Authors: Brodzinski, R.L. Report Title: The measurement of radiation exposure of astronauts by radiochemical techniques. Citation: Proceedings of the National Symposium on Natural and Manmade Radiation in Space (Warman, E.A., ed.). Washington, D.C.: NASA, p. 162-167, 1972. (NASA TM-X-2440). Radiation Type: Cr-51, Fe-59 No.: 5 Authors: Dunn, C.D.R.; Johnson, P.C. Report Title: Anemia of Space Flight. [Letter to the Editor] Citation: Blood 61: 1278-1279, 1983. Radiation Type: Cr-51 No.: 6 Authors: Fischer, C.L.; Johnson, P.C. Berry, C.A. Report Title: Red blood cell mass and plasma volume changes in manned space flight. Citation: Journal of the American Medical Association 200: 579-583, 1967. Radiation Type: I-125 No.: 7 Authors: Hoffler, G.W.; Johnson, R.L. Report Title: Apollo Flight Crew Cardiovascular Evaluations. Chapter 4. Citation: Biomedical Results of Apollo (Johnston, R.S.; Dietlein, L.F.; Berry, C.A., eds.). Washington, D.C.: NASA, p. 227-264, 1975. (NASA SP-368) Radiation Type: x-ray No.: 8 Authors: Hoffler, G.W.; Wolthuis, R.A.; Johnsonn, R.L. Report Title: Apollo space crew cardiovascular evaluations. Citation: Aerospace Medicine 45: 807-820, 1974. Radiation Type: x-ray No.: 9 Authors: Johnson, P.C.; Driscoll, T.B. Report Title: Section 2, The medical aspects of space flight seen from the viewpoint of nuclear medicine. Citation: Proceedings of the 1971 Manned Spacecraft Center Endocrine Program Conference, Houston, Texas (Leach, C.S., coordinator). Houston, TX: NASA Manned Spacecraft Center, 1972, p. 2-1 - 2-8. (NASA TM X-58093). Radiation Type: K-452, I-125, gamma Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VIII. Astronaut studies including space radiation exposure, tracer and scan studies, and assessment of activation of blood samples No.: 10 Authors: Johnson, P.C.; Driscoll, T.B.; LeBlanc, A.D. Report Title: Chapter 26, Blood volume changes. Citation: Biomedical Results from Skylab (Johnston, R.S.; Dietlein, L.F., eds.). Washington, D.C.: National Aeronautics and Space Administration, p. 235-241, 1977. (NASA SP-377). Radiation Type: C-14, Fe-59, I-125 No.: 11 Authors: Kimzey, S.L.; Johnson, P.C. Report Title: Hematological and immunological studies. Chapter 15. Citation: The Apollo-Soyuz Test Project: Medical Report (Nicogossian, A.E., Comp.). Washington, DC: NASA, p. 101-118, 1977. (NASA-SP-411) Radiation Type: No.: 12 Authors: Kimzey, S.L.; Johnson, P.C.; Ritzman, S.E.; Mengel, C.E. Report Title: Hematology and immunology studies: The second manned Skylab mission. Citation: Aviation, Space, and Environmental Medicine 47: 383-390, 1976. Radiation Type: C-14, Fe-59 No.: 13 Authors: Kimzey, S.L.; Fischer, C.L.; Johnson, P.C.; Ritzman, S.E.; Mengel, C.E. Report Title: Chapter 3, Hematology and immunology studies. Citation: Biomedical Results of Apollo (Johnston, R.S.; Dietlein, L.F.; Berry, C.A., eds.). Washington, D.C.: NASA, p. 197-226, 1975. (NASA SP-368) Radiation Type: C-14, Fe-59 No.: 14 Authors: Lanage, R.D.; Jones, J.B.; Johnson, P.C., Jr. Report Title: Comparative aspects of hematological responses in animal and human models in simulations of weightlessness and space flight. Citation: Physiologist 30(1, Suppl.): S113-S116, 1987. Radiation Type: Cr-51, I-125 No.: 15 Authors: Leach, C.S. Report Title: Biochemistry and endocrinology results. Chapter 14. Citation: The Apollo-Soyuz Test Project: Medical Report (Nicogossian, A.E., Comp.). Washington, DC: NASA, p. 87-100, 1977. (NASA-SP-411) Radiation Type: I-125, H-3, S-35, K-42 No.: 16 Authors: Leach, C.S. Report Title: Experiment 192. Fluid-electrolyte regulation during space flight. Citation: Interim report of SLS-1 experiment. Radiation Type: S-35 No.: 17 Authors: Leach, C.S.; Rambaut, P.C.; Johnson, P.C. Report Title: Adrenocortical responses of the Apollo 17 crew members. Citation: Aerospace Medicine 45: 529-534, 1974. Radiation Type: K-42 Page 2 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VIII. Astronaut studies including space radiation exposure, tracer and scan studies, and assessment of activation of blood samples No.: 18 Authors: Leach, C.S.; Inners, L.D.; Charles, J.B. Report Title: Changes in total body water during space flight. Citation: Results of the Life Sciences DSO's Conducted Aboard the Space Shuttle 1981-1986 (Bungo, M.W.; Bagian, T.M.; Bowman, M.A.; Levitan, B.M., eds.). Houston, TX: Space Biomedical Research Institute, NASA Lyndon B. Johnson Space Center, p. 49-53, 1987. Radiation Type: O-18 No.: 19 Authors: Leach, C.S.; Alexander, W.C.; Johnson, P.C. Report Title: Adrenal and pituitary response of the Apollo 15 crew members. Citation: Journal of Clinical Endocrinology and Metabolism 35: 642-645, 1972. Radiation Type: K-42, I-125 No.: 20 Authors: Leach, C.S.; Alexander, W.C.; Johnson, P.C. Report Title: Chapter 1, Endocrine, electrolyte, and fluid volume changes associated with Apollo missions. Citation: Biomedical Results of Apollo (Johnston, R.S.; Dietlein, L.F.; Berry, C.A., eds.). Washington, D.C.: National Aeronautics and Space Administration, p. 163-184, 1975. (NASA SP-368) Radiation Type: H-3, K-42, S-35, I-175 No.: 21 Authors: Leach, C.S.; Johnson, P.C. Report Title: Influence of spaceflight of erythrokinetics in man. Citation: Science 225: 216-218, 1984. Radiation Type: Space No.: 22 Authors: Leach, C.S.; Rambault, P.C. Report Title: Chapter 23, Biochemical responses of the Skylab crewmen: An overview. Citation: Biomedical Results from Skylab (Johnston, R.S.; Dietlein, L.F., eds.). Washington, D.C.: National Aeronautics and Space Administration, p. 204-216, 1977. (NASA SP-377) Radiation Type: S-35; K-42, 43;I-125 No.: 23 Authors: Leach, C.S.; Chen, J.P. Crosby, W.; Dunn, C.D.R.; Johnson, P.C.; Lange, R.D.; Larkin, E.; Report Title: Spacelab 1 Hematology Experiment (INS103): Influence of Space Flight on Erythrokinetics in Man. Citation: Houston: NASA, Johnson Space Center, 73 p., 1985. (NASA TM-58268) Radiation Type: Fe-59 Page 3 (rev 4/25/94) NASA RADIATION CITATIONS TABLE VIII. Astronaut studies including space radiation exposure, tracer and scan studies, and assessment of activation of blood samples No.: 24 Authors: Lockhart, L.H. Report Title: Cytogenetic studies of blood (Experiment M111). Citation: Proc. Skylab Life Sciences Symposium, August 27-29, 1974, JSC, Volume II (Johnston, R.S.; Dietlein, L.F., coordinators). Houston, TX: NASA Lyndon B. Johnson Space Center, p. 455-465, 1974. (NASA TM X-58154) Radiation Type: Space No.: 25 Authors: Lockhart, L.H. Report Title: Chapter 24: Cytogenetic studies of blood (Experiment M111). Citation: Biomedical Results from Skylab (Johnston, R.S.; Dietlein, L.F., eds). Washington, D.C.: National Aeronautics and Space Administration, p. 217-220, 1977. (NASA SP-377) Radiation Type: Space No.: 26 Authors: Mack, P.B.; LaChance, P.A.; Vose, G.P.; Vogt, F.B. Report Title: Bone demineralization of foot and hand of Gemini- Titan IV, V and VII astronauts during orbital flight. Citation: The American Journal of Roentgenology, Radium Therapy and Nuclear Medicine 100: 503-511, 1967. Radiation Type: x-ray No.: 27 Authors: Mack, P.B.; Vose, G.P.; Vogt, F.B.; LaChance, P.A. Report Title: Experiment M006. Bone demineralization. Citation: The Gemini Program. Biomedical Sciences Experiments Summary (Zeitler, E.O.; Rogers, T.G., comp.). Houston: NASA Manned Spacecraft Center, p. 45-85, 1971. (NASA TM X-58074) Radiation Type: x-ray No.: 28 Authors: Michels, D.B.; Friedman, P.J.; West, J.B. Report Title: Radiographic comparison of human lung shape during normal gravity and weightlessness. Citation: Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology 47(4): 851- 857, 1979. Radiation Type: x-ray No.: 29 Authors: Johnson, R.L.; Gowen, R.J. Report Title: Determination of cardiac size from chest roentgenograms following Skylab missions. Citation: The Proceedings of the Skylab Life Sciences Symposium, August 27-29, 1974. Johnson Space Center, Volume 2 (Johnston, R.S.; Dietlein, L.F., coordinators). Houston, Texas: NASA Lyndon B. Johnson Space Center, p. 785-793, 1974. (NASA TM X-58154) Radiation Type: x-ray No.: 30 Authors: Nicogossian, A.; Hoffler, G.W.; Johnson, R.L.; Gowen, R.J. Report Title: Determination of cardiac size following space missions of different durations: The second manned Skylab mission. Citation: Aviation, Space, and Environmental Medicine 47: 362-365, 1976. Radiation Type: x-ray Page 4 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VIII. Astronaut studies including space radiation exposure, tracer and scan studies, and assessment of activation of blood samples No.: 31 Authors: Nicogossian, A.E.; Hoffler, G.W.; Johnson, R.L.; Gowen, R.J. Report Title: Chapter 39, Determination of cardiac size from chest roentgenograms following Skylab missions. Citation: Biomedical Results from Skylab (Johnston, R.S.; Dietlein, L.F., eds.). Washington, D.C.: National Aeronautics and Space Administration p. 400-405, 1977. (NASA SP-377) Radiation Type: x-ray No.: 32 Authors: Nicogossian, A.E., LaPinta, C.K.; Burchard, E.C.; Hoffler, G.W.; Bartelloni, Report Title: Crew health. Chapter 3. Citation: The Apollo-Soyuz Test Project Medical Report (Nicogossian, A.E., comp.). Washington, D.C.: NASA, p. 11-24, 1977. (NASA SP-411) Radiation Type: x-ray No.: 33 Authors: Peterson, L. E.; Nachtwey, D. S. Report Title: Radiological Health Risks to Astronauts from Space Activities and Medical Procedures. Citation: Houston, TX: NASA Lyndon B. Johnson Space Center, 21 p., 1990. (NASA TM-102164) Radiation Type: all No.: 34 Authors: Rambaut, P.C.; Smith, M.C., Jr..; Mack, P.B.; Vogel, J.M. Report Title: Chapter 7, Skeletal response. Citation: Biomedical Results from Apollo (Johnston, R.S.; Dietlein, L.F.;Berry, C.A., eds.). Washington, D.C.: National Aeronautics and Space Administration p. 303-322, 1975. (NASA SP-368) Radiation Type: gamma No.: 35 Authors: Smith, M.C., Jr.; Rambaut, P.C.; Vogel, J.M.; Whittle, M.W. Report Title: Chapter 20, Bone mineral measurement - Experiment M078. Citation: Biomedical Results from Skylab (Johnston, R.S.; Dietlein, L.F., eds.). Washington, D.C.: National Aeronautics and Space Administration p. 183-190, 1977. (NASA SP-377) Radiation Type: K-42 No.: 36 Authors: Smith, M.C.; Rapp, R.M. Report Title: Food and Nutrition. Chapter 6. Citation: The Apollo-Soyuz Test Project Medical Report (Nicogossian, A.E., comp.). Washington, D.C.: NASA, p. 33-37, 1977. (NASA SP-411) Radiation Type: K-42 No.: 37 Authors: Tilton, F.E.; Degioanni, J.J.C.; Schneider, V.S. Report Title: Long-term follow-up of Skylab bone demineralization. Citation: Aviation, Space and Environmental Medicine 51: 1209-1213, 1980. Radiation Type: gamma Page 5 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE VIII. Astronaut studies including space radiation exposure, tracer and scan studies, and assessment of activation of blood samples No.: 38 Authors: Udden, M.M.; Driscoll, T.B.; Leach-Huntoon, C.S.; Alfrey, C.P. Report Title: Decreased effective production of red blood cells in man during spaceflight. Citation: Submitted for publication. Radiation Type: Cr-51, Fe-59, I-125 No.: 39 Authors: Vogel, J.M.; Rambaut, P.C.; Smith, M.C. Report Title: Bone Mineral Measurement from Apollo Experiment M- 078. Citation: Report to NASA, 40 p., 1974. (NASA TM X-58110) Radiation Type: gamma No.: 40 Authors: Vogel, J.M.; Whittle, M.W. Report Title: Bone mineral measurement - Experiment M078 Citation: The Proceedings of the Skylab Life Science Symposium, August 27-29, 1974, Johnson Space Center, Volume 1 (Johnston, R.S.; Dietlein, L.F., coordinators). Houston, Texas: NASA Lyndon B. Johnson Space Center, p. 387-401, 1974. (NASA TM X-58154) Radiation Type: No.: 41 Authors: Vogel, J.M.; Whittle, M.W. Report Title: Bone mineral content changes in the Skylab astronauts Citation: American Journal of Roentgenology 126: 1296-1297, 1976. Radiation Type: gamma No.: 42 Authors: Vogel, J.M.; Whittle, M.W. Report Title: Bone mineral changes: the second manned Skylab mission. Citation: Aviation, Space, and Environmental Medicine 47: 396-400, 1976. Radiation Type: gamma No.: 43 Authors: Vose, G.P. Report Title: Review of roentgenographic bone demineralization studies of the Gemini space flights. Citation: The American Journal of Roentgenology, Radium Therapy and Nuclear Medicine 121: 1-4, 1974. Radiation Type: x-ray Page 6 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts No.: 1 Authors: Barden, H.S; Mazess, R.B.; Rose, P.G.; McAweeney, W. Report Title: Bone mineral status measured by direct photon absorptiometry in institutionalized adults receiving long-term anticonvulsant therapy and multivitamin supplementation. Citation: Calcified Tissue International 31: 117-121, 1980. Radiation Type: gamma No.: 2 Authors: Block, J.E.; Friedlander, A.L.; Brooks, G.A.; Steiger, P.; Stubs, H.A.; Genant, H.K. Report Title: Determinants of bone density among athletes engage in weight-bearing and non weight-bearing activity. Citation: Journal of Applied Physiology 67: 1100-1105, 1989. Radiation Type: x-ray, gamma No.: 3 Authors: Cameron, J.R.; Mazess, R.B.; Wilson, C.R. Report Title: Skeletal Status and Soft Tissue Composition in Astronauts. Tissue and Fluid Changes by Radionuclide Citation: Annual Progress Report, 1974, Bone Mineral Laboratory, University of Wisconsin, 154 p., 1974. 9NASA-CR-140703) Radiation Type: gamma No.: 4 Authors: Convertino, V.A.; Doerr, D.F.; Flores, J.F.; Hoffler, G.W. Buchanan, P. Report Title: Leg size and muscle function associated with leg compliance. Citation: Journal of Applied Physiology 6f4(3): 1017-1021, 1988. Radiation Type: x-ray No.: 5 Authors: Convertino, V.A.; Doerr, D.F.; Mathes, K.L.; Stein, S.L.; Buchanan, P. Report Title: Changes in volume, muscle compartment, and compliance of the lower extremities in man following 30 days of exposure to simulated microgravity. Citation: Aviation, Space and Environmental Medicine 60: 653- 658, 1989 Radiation Type: x-ray No.: 6 Authors: Convertino, V.A.; Doerr, D.F.; Stein, S.L. Report Title: Changes in size and compliance of the calf after 30 days of simulated microgravity. Citation: Journal of Applied Physiology 66: 1509-1512, 1989. Radiation Type: x-ray No.: 7 Authors: Demling, R.H.; Mazess, R. B.; Witt, R.M.; Wolberg, W.H. Report Title: The study of burn wound edema using dichromatic absorptiometry. Citation: The Journal of Trauma 18: 124-128, 1978. Radiation Type: gamma Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts. No.: 8 Authors: Donaldson, C.L.; Hulley, S.B.; Rosen, S.N.; Friedman, R.J.; Vogel, J.M. Report Title: The influence of potassium phosphate (PO4) supplements on the calcium (Ca) balance & bone mineral changes of bed rest (BR) Citation: Clinical Research 18: 453, 1970. Radiation Type: gamma No.: 9 Authors: Donaldson, C.L.; Hulley, S.B.; Vogel, J.M.; Hattner, R.S.; Bayers, J.H.; McMillan, D.E. Report Title: Effect of prolonged bed rest on bone mineral. Citation: Metabolism 19: 1071-1084, 1970. Radiation Type: gamma No.: 10 Authors: Genant, H.K.; Gordan, G.S.; Hoffman, P.G., Jr. Report Title: Osteoporosis: Part 1. Advanced radiologic assessment using quantitative computed tomography - Medical Staff Conference, University of California, San Francisco. Citation: The Western Journal of Medicine 139: 75-84, 1983 Radiation Type: all No.: 11 Authors: Gluer, C. -C.; Reiser, U.J.; Davis, C.A.; Rutt, B.K.; Genant, H.K. Report Title: Vertebral mineral determination by quantitative computer tomography (QCT): Accuracy of single and dual energy measurements. Citation: Journal of Computer Assisted Tomography 12: 242- 258, 1988. Radiation Type: x-ray No.: 12 Authors: Hantman, D.A.; Vogel, J.M.; Donaldson, C.L.; Friedman, R.; Goldsmith, R.S.; Hulley, S.B. Report Title: Attempts to prevent disuse osteoporosis by treatment with calcitonin, longitudinal compression and supplementary calcium and phosphate. Citation: The Journal of Clinical Endocrinology and Metabolism 36: 845-858, 1973. Radiation Type: gamma Page 2 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts. No.: 13 Authors: Hoffler, G.W.; Baker, J.T.; Johnson, R.L.; Crosier, W. Report Title: NASA JSC - Baylor bed rest II. Cardiovascular studies. Lower body negative pressure. Citation: Report of 28-day Bedrest Simulation of Skylab, Vol. II. JSC/Methodist Hospital 28-day Bedrest Study, The Methodist Hospital, Houston, Texas. (Johnson, P.C.; Mitchell, C., comp.). Final Report, NASA Contract NAS 9-14578, p. F1-F105, 1977. (NASA-CR- 151354) Radiation Type: x-ray No.: 14 Authors: Hulley, S.B.; Vogel, J.M.; Donaldson, C.L.; Bayers, J.H.; Friedman, R.J.; Rosen, S.N. Report Title: The effect of supplemental oral phosphate on the bone mineral changes during prolonged bed rest. Citation: The Journal of Clinical Investigation 50: 2506- 2518, 1971. Radiation Type: gamma No.: 15 Authors: Lacy, J.L. Report Title: Multiwire gamma camera for radionuclide and radiographic imaging in the space environment. Citation: Workshop on Advances in NASA-Relevant, Minimally Invasive Instrumentation. Pasadena, CA: NASA, Jet Propulsion Laboratory, p. 1/17/1/28, 1985. (JPL D- 1942) Radiation Type: Ta-178 No.: 16 Authors: LeBlanc, A.; Schneider, V.; Krebs, J.; Evans, H.; Jhingran, S.; Johnson, P. Report Title: Spinal bone mineral after 5 weeks of bed rest. Citation: Calcified Tissue International 41: 259-261, 1987. Radiation Type: gamma No.: 17 Authors: LeBlanc, A.D.; Schneider, V.S.; Engelbretson, D.A.; Evans, H.J. Report Title: Precision of regional bone mineral measurements obtained from total-body scans. Citation: Journal of Nuclear Medicine 31: 43-45, 1990 Radiation Type: gamma No.: 18 Authors: LeBlanc, A.D.; Schneider, V.S.; Evans, H.J.; Engelbretson, D.A.; Krebs, J.M. Report Title: Bone mineral loss and recover after 17 weeks of bed rest. Citation: Journal of Bone and Mineral Research 5: 843-850, 1990 Radiation Type: gamma, x-ray Page 3 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts No.: 19 Authors: Mack, P.B. Report Title: Calcium loss studies during human bed rest: A preliminary report. Citation: Progress in Development of Methods in Bone Densitometry (Whedon, G.D.; Neuman, W.F.; Jenkins, D.W., eds.). Washington, D.C.: NASA, p. 169-177, 1966. (NASA SP-64) Radiation Type: x-ray, gamma No.: 20 Authors: Manatt, S.L.; Uhl, .W.W.; Werner, C.L.; Goldwhite, P.; Rutt, B.K.; Stebler, B.G.; Boyd, D.P.; Cann, C.E.; Genant, H.K. Report Title: Trabecular bone mineral measurements and computed tomo densitometer for more precise bone mineral measurements (Abstract). Citation: Aviation, Space, and Environmental Medicine 55: 472, 1984. Radiation Type: x-ray No.: 21 Authors: Mazess, R.B. Report Title: Noninvasive measurement of local bone in osteoporosis. Citation: Osteoporosis: Recent Advances in Pathogenesis and Treatment (DeLuca, H.F.; Frost, H.M.; Jee, W.S.S.; Johnston, C.C., Jr.; Parfitt, A.M., Eds.). Baltimore: University Park Press, p. 25-36, 1981. Radiation Type: gamma No.: 22 Authors: Mazess, R.B. Report Title: Photon absorptiometry. Citation: Non-invasive Measurements of Bone Mass and Their Clinical Application, Chapter 4 (Cohn, S.H., Ed.). Boca Raton, FL: CRC Press, p. 85-99, 1981. Radiation Type: gamma No.: 23 Authors: Mazess, R.B. Report Title: Chapter 6: The noninvasive measurement of skeletal mass. Citation: Bone and Mineral Research, Annual 1 (Peck, W.A., Ed.). Amsterdam: Excerpta Medica, p. 223-279, 1983. Radiation Type: No.: 24 Authors: Mazess, R.B. Report Title: Skeletal and Body Composition Evaluation. Citation: Final Report, NASA Contracts NASA-Y-NGR-50-002-051 and NAG2-166, 1966-1982, 86 p., 1983. (NASA-CR- 166465) Radiation Type: Te-99m No.: 25 Authors: Mazess, R.B. Report Title: Non-invasive measurement of bone. Citation: Osteoporosis II (Barzel, U.S., Ed.). New York: Grune & Stratton, p. 5-26, 1979. Radiation Type: photon, x-ray, gamma Page 4 (rev. 4/25/95) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts. No.: 26 Authors: Mazess, R.B. Report Title: Measurement of skeletal status by noninvasive methods (Editorial). Citation: Calcified Tissue International 28: 89-92, 1979. Radiation Type: gamma No.: 27 Authors: Mazess, R.B.; Peppler, W. Report Title: Total body bone mineral by photon absorptiometry. Citation: Calcified Tissue Research 22: 452-453, 1977. Radiation Type: gamma No.: 28 Authors: Mazess, R.B.; Peppler, W.W.; Chesney, R.W.; Lange, T.A.; Lindgren, U.; Smith, E., Jr. Report Title: Total body and regional bone and mineral and lean body mass by dual-photon absorptiometry in metabolic bone disease. Citation: Calcified Tissue International 36: 8-13, 1984. Radiation Type: gamma No.: 29 Authors: Mazess, R.B.; Peppler, W.W.; Chestnut, C.H., III; Nelp, W.B.; Cohn, S.H.; Zanzi, I. Report Title: Total body bone mineral and lean body mass by dual- photon absorptiometry. II. Comparison with total body by neutron activation analysis. Citation: Calcified Tissue International 33(4): 361-363, 1981a. Radiation Type: gamma, n No.: 30 Authors: Mazess, R.B.; Peppler, W.W.; Gibbons, M. Report Title: Total body composition by dual-photon (153 Gd) absorptiometry. Citation: The American Journal of Clinical Nutrition 40: 834- 839, 1984 Radiation Type: gamma No.: 31 Authors: Mazess, R.B.; Peppler, W.W.; Harrison, J.E.; McNeil, K.G. Report Title: Total body bone mineral and lean body mass by dual- photon absorptiometry. III. Comparison with trunk calcium by neutron activation analysis. Citation: Calcified Tissue International 33(4): 365-368, 1981b Radiation Type: gamma, n No.: 32 Authors: Mazess, R.B.; Young, D. Report Title: Measurement of spine and total body mineral by dual-photon absorptiometry. Citation: Space Physiology, Colloquium, Toulouse, France, March 1-4, 1983, Proceedings. Toulouse, France: Cepadues-Edition, p. 209-214, 1983. Radiation Type: gamma Page 5 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts. No.: 33 Authors: Murray, R.G.; Peshock, R.M.; Parkey, R.W.; Bonte, F.J.; Willerson, J.T.; Blomqvist, C.G. Report Title: ST isopotential precordial surface maps in patients with acute myocardial infarction. Citation: Journal of Electrocardiology 12(1): 55-64, 1979. Radiation Type: Te-99m No.: 34 Authors: Peppler, W.W.; Mazess, R.B. Report Title: Total body bone mineral and lean body mass by dual-photon absorptiometry. I. Theory and measurement procedure Citation: Calcified Tissue International 33(4) 353-359, 1981. Radiation Type: gamma No.: 35 Authors: Powell, M.R.; Kolb, F.O.; Genant, H.K.; Cann, C.E.; Stebler, B.G. Report Title: Comparison of dual absorptiometry and quantitative computed tomography of the lumbar spine in the sam subjects. Citation: Clinical Disorders of Bone and Mineral Metabolism (Fram, B.; Potts, J.T., Jr., Eds.). Amsterdam: Excerpta Medica, p. 58-61, 1983. Radiation Type: x-ray gamma No.: 36 Authors: Rambaut, P.C.; Dietlein, L.F.; Vogel, J.M.; Smith, M.C., Jr. Report Title: Comparative study of two direct methods of bone mineral measurement. Citation: Aerospace Medicine 43: 646-650, 1972. Radiation Type: x-ray, gamma No.: 37 Authors: Reinbold, W.-D.; Genant, H.K.; Reiser, U.J.; Harris, S.T.; Ettinger, B. Report Title: Bone mineral content in early-postmenopausal and postmenopausal osteoporotic women: Comparison of measurement methods. Citation: Radiology 160: 469-478, 1986. Radiation Type: x-ray, gamma No.: 38 Authors: Schneider, V.S.; Hinderling, T.; Vogel, J.M.; Rambaut, P. Report Title: CT125I gamma ray densitometry (CT scanner): noninvasive measurement of trabecular bone mineral. Citation: Proceedings of International Workshop on Bone and Soft Tissue Densitometry Using Computed Tomography, San Francisco, CA, June 7-9, 1979. Journal of Computer Assisted Tomography 3: 847-848, 1979. Radiation Type: gamma Page 6 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts. No.: 39 Authors: Schneider, V.S.; Hulley, S.B.; Donaldson, C.L.; Vogel, J.M.; Rosen, S.N.; Hantman, D.A.; Lockwood, D.R.; Seid, D.; Hyatt, K.H.; Jacobson, L.B. Report Title: Prev. of Bone Mineral Chgs Ind. by Bedrest; Mod. by (1) Static Comp. Simul. Wt Bearing; (2) Comb. Sup. of Oral Cal. & Phos.; (3) Calcitonin Injections; (4) Oscillating Comp.; (5) The Oral Diophosphonate-disodium Etidronate; (6) Lower Body Neg. Pressure Citation: NASA Terminal Report, Contract No. T-81070, 55 p., 1975 (NASA-CR-141453) Radiation Type: x-ray, gamma, Ca-47 No.: 40 Authors: Selzer, R.H. Report Title: Visualization of coronary arteries from intravenous angiograms. Citation: Workshop on Advances in NASA-Relevant, Minimally Invasive Instrumentation. Pasadena, CA: NASA, Jet Propulsion Laboratory, p. 1/29- 1/42, 1985. (JPL D-1942) Radiation Type: x-ray No.: 41 Authors: Selzer, R.H.; Shircore, A.; Lee, P.L.; Hemphill, L.; Blankenhorn, D.H. Report Title: A second look at quantitative coronary angiography: Some unexpected problems. Citation: State of the Art in Quantitative Coronary Arteriography (Reiber, J.H.C., Serrys, P.W., Eds.). Dordrecht, The Netherlands: Martinus- Nyhoff, p. 125-143, 1986. Radiation Type: x-ray No.: 42 Authors: Selzer, R.H.; Blankenhorn, D.H.; Brooks, S.H.; Crawford, D.W.; Cashin, W.L. Report Title: Computer assessment of atherosclerosis from angiographic images. Citation: IEEE Transactions on Nuclear Science NS- 29(3):1198-1207, 1982. Radiation Type: x-ray No.: 43 Authors: Siebes, M.; D'Argenio, D.Z.; Selzer, R.H. Report Title: Computer assessment of hemodynamic severity of coronary artery stenosis from angiograms. Citation: Computer Methods and Programs in Biomedicine 21: 143-152, 1985. Radiation Type: x-ray Page 7 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts. No.: 44 Authors: Steiger, P.; Block, J.E.; Steiger, S.; Heuck, A.F.; Freidlander, A.; Ettinger, B.; Harris, S.T.; Gluer, C.-C.; Genant, H.K. Report Title: Spinal bone mineral density measured with quantitative CT: Effect of region of interest, vertebral level, and technique. Citation: Radiology 175: 537-543, 1990. Radiation Type: x-ray No.: 45 Authors: Steiger, P.; Steiger, S.; Ruegsegger, P.; Genant, H.K. Report Title: Two- and three-dimensional quantitative image evaluation techniques for densitometry and volumetrics in longitudinal studies. Citation: Osteoporosis: Update 1987 (Genant, H.K., Ed.). Berkeley, CA: University of California Press, p. 171-180, 1987. Radiation Type: e+ No.: 46 Authors: Texas Woman's University. Report Title: Bone Density Studies of Bed Rest Subjects at the Public Health Service Hospital in San Francisco, by the Texas Woman's University Radiographic Method. Citation: Final Report, Texas Woman's University, Denton, Texas, NAS 9-9427, 153 p., 1971. (NASA-Cr-114784) Radiation Type: x-ray, gamma No.: 47 Authors: Verani, M.S.; Gaeta, J.; LeBlanc, A.D.; Poliner, L.R.; Phillips, L.; Lacy, J.L.; Thornby, J.I.; Roberts, R. Report Title: Validation of left ventricular volume measurements by radionuclide angiography. Citation: Journal of Nuclear Medicine 26(12): 1394-1401, 1904. Radiation Type: Te-99m No.: 48 Authors: Vogel, J.M. Report Title: Changes in bone mineral content of the oscalcis induced by prolonged bed rest. Chapter 19. Citation: Hypogravic and Hypodynamic Environments (Murray, R.H.; McCally, M., eds.). Washington, D.C.: NASA, p. 261-269, 1971. (NASA SP-269) Radiation Type: gamma Page 8 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE IX. Studies of bone and mineral changes in volunteers other than astronauts. No.: 49 Authors: Vogel, J.M.; Cline, J.W.; Harrison, J.F.; Ulloa, G.A.; McDonald, R.J. Report Title: Microcomputer based dual energy photon absorptiometric bone mineral analyzer (VCH). Citation: IEEE Transactions on Nuclear Science NS-26: 576-582, 1979. Radiation Type: No.: 50 Authors: Vogt, F.B.; Mack, P.B.; Beasley, W.G.; Spencer, W.A.; Cardus, D.; Vallbona, C. Report Title: The Effect of Bedrest on Various Parameters of Physiological Function. Part XII. The Effect of Bedrest on Bone Mass and Calcium Balance. Citation: Report prepared under Contract No. NAS 9-1461 by Texas Institute for Rehabilitation and Research, Houston, Texas. Washington, D.C.: NASA, 55 p., 1965. (NASA-CR-182) Radiation Type: x-ray, gamma No.: 51 Authors: Vose, G.P.; Hurxthal, L.M. Report Title: X-ray density changes in the human heel during bed rest. Citation: The American Journal of Roentgenology, Radium Therapy and Nuclear Medicine 106: 486-490, 1969. Radiation Type: x-ray No.: 52 Authors: Witt, R.M.; Mazess, R.B. Report Title: Photon absorptiometry of soft tissue and fluid content: the method and its precision and accuracy. Citation: Physics in Medicine and Biology 23: 620-629, 1978. Radiation Type: gamma No.: 53 Authors: Wolberg, W.H.; Witt, R.M.; Moylan, J.A.; Mazess, R.B. Report Title: Soft-tissue fluid determination by dichromatic absorptiometry. Citation: Archives of Surgery 112: 462-466, 1977. Radiation Type: gamma Page 9 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 1 Authors: Baisch, F.; Beck, L.; Maass, H.; Heer, M.; Plath, G.; Blomqvist, G.; Gaffney, A.; Buckey, J.; Hillebrecht, A.; Schulz, H.; Meyer, M.; Kropp, J.; Ten Harkel, D.J.; Karemaker, J.; Patat, F.; Arbeille, Ph. Report Title: Effects of a 10-day period of 6 degree head down tilt (HDT) Citation: Physiologist 33(1, Suppl.): S163-S164, 1990. Radiation Type: Cr-51 No.: 2 Authors: Blackshear, J.L.; Garnic, D.; Williams, G.H.; Harrington, D.P.; Hollenberg, N.K.; Report Title: Exaggerated renal vasodilator response to calcium entry blockade in first-degree relatives of essential hypertensive subjects. Citation: Hypertension 9(4): 384-389, 1987. Radiation Type: Xe-133 No.: 3 Authors: Bohnn, B.J.; Hyatt, K.H.; Kamenetsky, L.G.; Calder, B.E.; Smith, W.M. Report Title: Prevention of bedrest induced orthostatism by 9-alpha-fluorohydrocortisone. Citation: Aerospace Medicine 41: 495-499, 1970. Radiation Type: I-125 No.: 4 Authors: Breslau, N.A.; Brinkley, L.; Hill, K.D.; Pak, C.Y.C Report Title: Relationship of animal protein rich diet to kidney stone formation and calcium metabolism. Citation: Journal of Clinical Endocrinology and Metabolism 66(1): 140-146, 1988. Radiation Type: Ca-47 Page 1 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 5 Authors: Bungo, M.W.; Leland, O.S., Jr. Report Title: Discordance of exercise thallium testing with coronary arteriography in patients with atypical presentations. Citation: Chest 83: 112-116, 1983. Radiation Type: TI-201 No.: 6 Authors: Donaldson, C.L.; McMillan, D.E.; Hulley, S.B.; Hattner, R.S.; Bayers, J.H. Report Title: The effects of long-term bed rest on mineral metabolism. Citation: Hypogravic and Hypodynamic Environments (Murray, R.H.; McCally, M., eds.). Washington, D.C.: NASA, p. 249-260, 1971. (NASA SP-269) Radiation Type: I-131, gamma No.: 7 Authors: Dunn, C.D.R.; Lange, R.D.; Kimzey, S.L.; Johnson, P.C.; Leach, C.S. Report Title: Implications of the Etiology of the Anemia of Space Flight From a Study of Erythropoietin (Ep) Titers in Subjects Exposed to Prolonged Bedrest. Citation: Preprints of 1983 Annual Scientific Meeting, Aerospace Medical Association, Houston, TX, May 23-26, 1983. Washington, DC: Aerospace Medical Association, p. 208-209, 1983. Radiation Type: Cr-51, I-125 No.: 8 Authors: Dunn, C.D.R.; Johnson, P.C.; Leach, C.S. Report Title: Fluid shifts and erythropoiesis: Relevance to the "anemia" of space flight. Citation: Physiologist 25(6, Suppl.): S79-S80, 1982. Radiation Type: Cr-51, I-125 No.: 9 Authors: Fortney, S.; Drew, H.; LaFrance, N. Report Title: Plasma Volume Responses During Bedrest in Health Women. Citation: Preprints of 1983 Annual Scientific Meeting, Aerospace Medical Association, Houston, TX, May 23-26, 1983. Washington DC: Aerospace Medical Association, p. 245-246, 1983. Radiation Type: Te-99m No.: 10 Authors: Fuller, J.H.; Bernauer, E.M.; Adams, W.C.; Report Title: Renal function, water and electrolyte exchange during bed rest with daily exercise. Citation: Aerospace Medicine 41: 60-72, 1970. Radiation Type: K-40, I-125 Page 2 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 11 Authors: Gaffney, F.A.; Buckey, J.C.; Lane, L.D.; Hillebrecht, A.; Schulz, H.; Meyer, M.; Baisch, F.; Beck, L.; Heer, M.; Maass, H.; Arbeille, Ph.; Patat, F.; Blomqvist, C.G. Report Title: The effects of a 10-day period of head-down title on the cardiovascular responses to intravenous saline loading. Citation: Physiologist 33(1, Suppl.): S171-S172, 1990. Radiation Type: Cr-51 No.: 12 Authors: Gaffney, F.A.; Nixon, J.V.; Karlsson, E.S.; Campbell, W.; Dowdey, A.B.C.; Blomqvist, C.G. Report Title: Cardiovascular deconditioning produced by 20 hours of bedrest with head-down tile (-5 degree) in middle-aged healthy men. Citation: American Journal of Cardiology 56: 634-638, 1985. Radiation Type: Cr-51, I-131 No.: 13 Authors: Goldwater, D.; Polese, A.; Montgomery, L.; London, L.; Johnson, P.; Yuster, D.; Sandler, H. Report Title: Comparison of Orthostatic Intolerance Following Horizontal or -6 degrees Head-down Bed Rest Simulation of Weightlessness. Citation: Preprints of 1980 Annual Scientific Meeting, Aerospace Medical Association, Anaheim, CA, May 12-15, 1980. Washington, DC: Aerospace Medical Association, p. 28-29, 1980. Radiation Type: I-125, Cr-51 No.: 14 Authors: Greenleaf, J.E.; Hinghofer-Szalkay, H. Report Title: Plasma Volume Methodology: Evans Blue, Hemoglobin-Hematocrit, and Mass Density Transformations. Citation: Moffett Field, CA: NASA, Ames Research Center, 24 p., 1985. (NASA-TM-86834) Radiation Type: N-15 No.: 15 Authors: Hollenberg, N.K.; Meyerovitz, M.; Harrington, D.P.; Sandor, T. Report Title: Influence on norepinephrine and angiotensin II on vasomotion of renal blood supply i humans. Citation: American Journal of Physiology 252: H941- H944, 1987. Radiation Type: Xe-133 Page 3 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 16 Authors: Hollenbereg, N.K.; Sandor, T. Report Title: Vasomotion of renal blood flow in essential hypertension: Oscillations in xenon transit. Citation: Hypertension 6: 579-585, 1984. Radiation Type: Xe-133 No.: 17 Authors: Hollenberg, N.K.; Sandor, T.; Holtzman, E.; Meyerovitz, M.F.; Harrington, D.P.; Report Title: Renal vasomotion in essential hypertension: Influence of vasodilators. Citation: Hypertension 14(1): 9-13, 1989. Radiation Type: Xe-133 No.: 18 Authors: Hyatt, K.H. Report Title: Hemodynamic and body fluid alterations induced by bedrest. Chapter 14. Citation: Hypogravic and Hypodynamic Environments (Murray, R.H.; McCally, M., eds.). Washington, D.C.: NASA, p. 187-209, 1971. (NASA SP-269) Radiation Type: I-125, 131, CR-51, H-3, Br-82 No.: 19 Authors: Hyatt, K.H.; Jacobson, L.B.; Schneider, V.S. Report Title: Comparison of 70 degree tilt, LBNP, and passive standing as measures of orthostatic tolerance. Citation: Aviation, Space and Environmental Medicine 46: 801-808, 1975. Radiation Type: I-125 No.: 20 Authors: Hyatt, K.H.; Smith, W.M.; Vogel, J.M.; Sullivan, R.W.; Vetter, W.R.; Calder, B.E.; Bohnn, B.J.; Haughton, V.M. Report Title: A Study of the Role of Extravascular Dehydration in the Production of Cardiovascular Deconditioning by Simulated Weightlessness (Bedrest). Citation: Part I. Final Report, NASA Contract T- 68099(G), 73 p., 1970. (NASA-CR-114808) Radiation Type: I-125, Br-82, C-51, H-3 No.: 21 Authors: Hyatt, K.H.; West, D.A. Report Title: Reversal of bedrest-induced orthostatic intolerance by lower body negative pressure and saline. Citation: Aviation, Space, and Environmental Medicine 48: 120-124, 1977. Radiation Type: I-125 Page 4 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 22 Authors: Jacobson, L.B.; Hyatt, K.H.; Sullivan, R.W.; Cantor, S.A.; Sandler, H.; Rositano, S.A.; Mancini, R. Report Title: Evaluation of +Gz Tolerance Following Simulated Weightlessness (Bedrest). Citation: NASA Technical Memorandum, 96 p., 1974. (NASA TM X-62311) Radiation Type: I-125, Br-82, Cr-51, H-3 No.: 23 Authors: Johnson, P.C.; Driscoll, T. Report Title: Red cell mass and body volume changes after 28 days of bedrest. Citation: Report of 28-day Bedrest Simulation of Skylab, Vol. II. JSC/Methodist Hospital 28-day Bedrest Study, The Methodist Hospital, Houston, Texas. (Johnson, P.C.; Mitchell, C., comp.). Final Report NASA Contract NAS 9- 14578, p. E1-E29, 1977. (NASA-CR-151354) Radiation Type: I-125, S-35, Cr-51, Fe-59 No.: 24 Authors: Johnson, P.C.; Driscoll, T. Report Title: Red cell mass and body volume changes after 14 days of bedrest. Citation: Report of 14-day Bedrest Simulation of Skylab (Johnson, P.C.; Mitchell, C., comp.). Final Report NASA Contract NAS 9-14578, p.149-170, 1976. (NASA-CR-147758) Radiation Type: H-3, S-35, K-43, Cr-51, Fe-59, I-125 No.: 25 Authors: Johnson, P.C.; Driscoll, T.B.; Alexander, W.C.; Lambertsen, C.J. Report Title: Body fluid volume changes during a 14-day continuous exposure to 5.2% o2 in N2 at pressure equivalent to 100 FSW (4 ata). Citation: Aerospace Medicine 44: 860-863, 1973. Radiation Type: H-3, S-35, Cr-51, Fe-59, I-125 No.: 26 Authors: Johnson, P.C.; Driscoll, T.B.; Carpentier, W.R. Report Title: Vascular and extravascular fluid changes during six days of bedrest. Citation: Aerospace Medicine 42: 875-878, 1971. Radiation Type: C-14, Cr-51, I-125, H-3, S-35 Page 5 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 27 Authors: Johnson, P.C.; Driscoll, T.B.; Fischer, C.L. Report Title: Blood volume changes in divers of Tektite 1. Citation: Aerospace Medicine 42: 423-426, 1971. Radiation Type: C-14, Cr-51, I-125 No.: 28 Authors: Johnson, P.C.; LeBlanc, A.; Deboer, L.; Jhingran, S. Report Title: Evaluation of Thallium-201 Scanning for detection of Latent Coronary Artery Disease. Citation: Final report, Contract NAS9-15119. Methodist Hospital, Houston, TX 18 p., 1978 (NASA-CR- 151662) Radiation Type: TI-201 No.: 29 Authors: Krebs, J.M.; Schneider, V.S.; Evans, H.; Kuo, M.C.; LeBlanc, A.D. Report Title: Energy absorption, lean body mass, and total body fat changes during 5 weeks of continuous bed rest. Citation: Aviation, Space, and Environmental Medicine 61: 314-318, 1990. Radiation Type: K-40 No.: 30 Authors: Leach, C.S. Report Title: Biochemical results. Citation: Report of 14-day Bedrest Simulation of Skylab (Johnson, P.C.; Mitchell, C., comp.). Final Report NASA Contract NAS 9-14578, p. 171-225, 1976. (NASA-CR- 147758) Radiation Type: H-3, S-35, i-125, K-42 No.: 31 Authors: Leach, C.S.; Johnson, P.C.; Driscoll, T.B. Report Title: Effects of bedrest and centrifugation of humans on serum thyroid function tests. Citation: Aerospace Medicine 43: 400-402, 1972. Radiation Type: I-125 No.: 32 Authors: Mack, P.B.; Montgomery, K.B. Report Title: Study of nitrogen balance and creatine and creatine excretion during recumbency and ambulation of five you adult human males. Citation: Aerospace Medicine 44: 739-746, 1973. Radiation Type: Ca-47, x-ray No.: 33 Authors: Moore-Ede, M.C.; Meguid, M.M.; Fitzpatrick, G.F.; Boyden, C.M.; Ball, M.R. Report Title: Circadian variation in response to potassium infusion. Citation: Clinical Pharmacology and Therapeutics 23: 218-227, 1978. Radiation Type: K-42, x-ray Page 6 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 34 Authors: Nixon, J.V.; Murray, R.G.; Bryant, C.; Johnson, R.L., Jr.; Mitchell, J.H.; Holland, O.B.; Gomez-Sanchez, C.; Vergne-Marini, P.; Blomqvist, C.G. Report Title: Early cardiovascular adaptation to simulated zero gravity. Citation: Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology 46: 541- 548, 1979. Radiation Type: Cr-151, I-125 No.: 35 Authors: Pace, N.; Grunbaum, B.W.; Kodama, A.M.; Price, D.C. Report Title: In Vivo Measurement of Human Body Composition. Citation: Semi-annual Status Report No. 5, University of California, Berkeley, White Mountain Research Station, July 1, 1974 - December 31, 1974, NASA grant NGR 05-003-470, 76 P., 1975. (NASA-CR-143375) Radiation Type: H-3, Cr-51 No.: 36 Authors: Shangraw, R.E.; Stuart, C.A.; Prince, M.J.; Peters, E.J.; Wolfe, R.R. Report Title: Insulin responsiveness of protein metabolism in vivo following bedrest in humans. Citation: American Journal of Physiology 255: E548-E558, 1988. Radiation Type: C-13 No.: 37 Authors: Siri, W.E. Report Title: Preliminary Report on Studies of Erythropoiesis and Adrenal-Cortical Function on Mt. Everest. Citation: Semiannual Report - Biology and Medicine, Spring 1963, Donner Laboratory and Donner Pavillion, Lawrence Radiation Laboratory, Univ. of California, Berkeley, California (Lawrence, J.H.; Neville, T., eds.), p. 1-11, 1963. (UCRL-11033, NASA-CR-55512). Radiation Type: Fe-59 No.: 38 Authors: Spears, C.P.; Hyatt, K.H.; Vogel, J.M.; Bangfitt, S.B. Report Title: Unified method for serial study of body fluid compartments. Citation: Aerospace Medicine 45: 274-278, 1974. Radiation Type: I-125, H-3, Br-82, Cr-51 Page 7 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 39 Authors: Stein, T.P.; Settle, R.G.; Albina, J.A.; Dempsey, D.T.; Melnick, G. Report Title: Metabolism of nonessential 15N-labeled amino acids and the measurement of human whole-body protein synthesis rates. Citation: Journal of Nutrition 116: 1651-1659, 1986. Radiation Type: N-15 No.: 40 Authors: Stuart, C.A.; Shangraw, R.E.; Peters, E.J.; Wolfe, R.R. Report Title: Effect of dietary protein on bed-rest-related changes in whole-body-protein synthesis. Citation: American Journal of Clinical Nutrition 52: 509-514, 1990. Radiation Type: C-13 No.: 41 Authors: Stuart, C.A.; Shangraw, R.E.; Prince, M.J.; Peters, E.J.; Wolfe, R.R. Report Title: Bed-rest-induced insulin resistance occurs primarily in muscle. Citation: Metabolism 37(8): 802-806, 1988. Radiation Type: H-3 No.: 42 Authors: van Beaumont, W.; Greenleaf, J.E.; Juhos, L. Report Title: Disproportional changes in hematocrit, plasma volume, and proteins during exercise and bed rest. Citation: Journal of Applied Physiology 33: 55-61, 1972. Radiation Type: I-131 No.: 43 Authors: Vogt, F.B.; Mack, P.B.; Johnson, P.C. Report Title: Effect of garments which provide work loads in preventing the cardiovascular deconditioning of bedrest. Citation: Aerospace Medicine 38: 1134-1137, 1967. Radiation Type: I-125, x-ray No.: 44 Authors: Vogt, F.B.; Mack, P.B.; Johnson, P.C. Report Title: Tilt table response and blood volume changes associated with thirty days of recumbency. Citation: Aerospace Medicine 37: 771-777, 1966. Radiation Type: I-125, x-ray No.: 45 Authors: Vogt, F.B.; Mack, P.B.; Johnson, P.C.; Wade, L., Jr. Report Title: Title table response and blood volume changes associated with fourteen days of recumbency. Citation: Aerospace Medicine 38: 43-48, 1967. Radiation Type: I-131, x-ray No.: 46 Authors: Vogt, F.B.; Johnson, P.C. Report Title: Effectiveness of extremity cuffs or leotards in preventing or controlling the cardiovascular deconditioning of bedrest. Citation: Aerospace Medicine 38: 702-707, 1967. Radiation Type: I-125 Page 8 (rev. 4/25/94) NASA RADIATION CITATIONS TABLE X. Studies using radiopharmaceutical tracers (not astronauts), including bedrest studies. No.: 47 Authors: Vogt, F.B.; Johnson, P.C. Report Title: Plasma volume and extracellular fluid volume change associated with 10 days bed recumbency. Citation: Aerospace Medicine 38: 21-25, 1967. Radiation Type: H-3; Cr-51; S-35; I-125, 131 No.: 48 Authors: Vogt, F.B.; Spencer, W.A.; Cardus, D.; Valbona, C. Report Title: The Effect of Bedrest on Various Parameters of Physiological Function. Part XI. The Effect of Bedrest on Blood Volume, Urinary Volume, and Urinary Electrolyte Excretion. Citation: Report prepared under Contract No. NAS 9-1461 by Texas Institute for Rehabilitation and Research, Houston, Texas. Washington, D.C.: NASA, 32 p., 1965. (NASA-CR-181) Radiation Type: I-131, X-RAY No.: 49 Authors: Young, D.R.; Pelligra, R.; Shapira, J.; Adachi, R.R.; Skrettingland, L. Report Title: Glucuse oxidation and replacement during prolonged exercise in man. Citation: Journal of Applied Physiology 23: 734-741, 1967. Radiation Type: C-14 No.: 50 Authors: Zager, P.G.; Luetscher, J.A.; Hsueh, W.A.; Chavarri, M.R.; Dowdy, A.J. Report Title: Adrenocorticotropin-stimulated secretion of aldosterone and cortisol, computed from plasma and red blood cell measurements. Citation: Journal of Clinical Endocrinology And Metabolism 48: 441-450, 1979. Radiation Type: H-3, Ca-14, I-131 Page 9