DISCLAIMER The following is a staff memorandum or other working document prepared for the members of the Advisory Committee on Human Radiation Experiments. It should not be construed as representing the final conclusions of fact or interpretation of the issues. All staff memoranda are subject to revision based on further information and analysis. For conclusions and recommendations of the Advisory Committee, readers are advised to consult the Final Report to be published in 1995. TAB N MEMORANDUM TO: Members of the Advisory Committee on Human Radiation Experiments FROM: Advisory Committee Staff DATE: August 31, 1994 RE: Permissible Doses Conference held at Chalk River, Ontario, September 1949 Over the years a number of conferences among representatives of the United States, Canada and the United Kingdom have been held at Chalk River, the site of Canadian nuclear laboratories. The conference held in September 1949 was crucial in arriving at an agreement on the basic parameters for developing safety standards for radiation exposure. The document enclosed, provided to us by the Institute for Energy and Environmental Research, is a summary of that conference by its secretary, G.E. McMurtie. It provides a detailed description of the issues raised and the agreements reached. The report is quite detailed and at times technical. However, even a brief skimming allows one to contrast the discussion of safety issues in 1949 with modern discussions. The list of topics covered also provides an overview of the many areas in which standardization was needed in order to develop broadly applicable guidelines. As a guideline to reading, the topics covered are: 1. Standard Man 4 a. Mass of Organs 4 b. Chemical Composition 6 c. Applied Physiology 7 (i) Water Balance (ii) Respiration (iii) Duration of Occupational Exposure (iv) Duration of "Lifetime" for Non-occupational Exposure d. Standardized Terminology 8 e. Retention of Particulate Matter in the Lungs 8 1 2. Relative Biological Efficiency 9 a. Beta particles b. Protons c. Alpha Particles d. Fast Neutrons e. Slow Neutrons 3. Permissible exposure to External Radiation 11 a. Whole body, long continued exposure b. Whole body, single exposure c. Hands, long continued exposure d. Head, long continued exposure 4. Permissible Exposure to Internal Irradiation 13 Group I (Radium, Radon, Uranium, Plutonium, Thorium, Polonium) 15 Group II (Fission Products) 18 Group III (H 3, C 14, Na 24, P 32, S 35, A 41, Sr 89, Sr 90, I 131, Co 60) 19 a. Amount of radioisotope permitted fixed in the body b. Concentration of radioisotope permitted in inspired air c. Concentration of radioisotope permitted in drinking water 2 L:\BRFBOOKS\BOOK6\9409TABO.WPD