Attachment 2




Type of institution: national laboratory (Government-owned, 
contractor-operated) and uranium processing center and associated
research facilities

Mission:  processing and associated biomedical research; general 
research; and cancer research 

Links: DOD/Armed Forces Special Weapons Project;  NASA;  PHS; 
associated universities; contractor operators;  radioisotope 
licensees;  extramural contractors and grantees

Experiments or other radiation research:
*    Manhattan Project fuel processing began in 1942; radioisotope 
     distribution began in 1947; research institute began operating 
     cancer research hospital in 1950

Secret or classified research:  Yes, but extent and nature unknown
*    types of experiments: plutonium injection (1945); total body 
     irradiation (1950-1970's); cancer therapy with short-lived 
     radionuclides (1950 - ?); supported extramural contractor 
     performing uranium experiments (1950's); supported prisoner 
     experiments (date unknown); regulated extramural radioisotope use 
     through licensing process (1946 - ?); environmental releases 
     (late 1940's); experiments of opportunity in industrial 
     accidents.
*    number of experiments: unknown


AVAILABLE DATA 

Experiments: 
*    Histories of research program:  partially collected, others 
     should be readily obtainable
*    "Start/stop" documents for specific experiments/programs:  
     partially collected, others should be readily obtainable
*    Publications or reports for specific experiments/programs :  
     partially collected, others should be readily obtainable

Program:
*    Record of chains of command for program decisions and review :  
     partially collected, others should be readily obtainable; DOD 
     records on AFSWP presence not yet explored
*    Funding source: AEC with NASA funding of TBI; DOD funding 
     suspected but not yet determined; records requested but not yet 
     produced

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Was there secret or classified funding? Yes, but extent, source and 
purpose not yet explored
Consent:  What was the extant consent policy? 
          AEC consent memorandum required informed consent in the 
          presence of a witness; cancer hospital used patient 
          admissions brochure and written release
*    The  institutional form for the policy: Multiple oversight, 
     including AEC isotope licensing committee; human use committee at 
     cancer hospital after 1966
*    Records of implementation: Waiver/release form, brochure; Isotope 
     Division records not located

Subject selection: 
     Patients at cancer hospital selected based on research 
suitability; otherwise not yet known

OVERSIGHT

Multiple committees:  ORINS  Advisory, Advisory Committee on Biology 
and Medicine, Human Use subcommittee for isotope licensing; actual 
practical oversight not yet established

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