Attachment 4 UNIVERSITY OF CALIFORNIA AT LOS ANGELES (UCLA) OVERVIEW Type of institution: Branch of state university including medical school; affiliated with VA hospital Mission: Atomic Energy Project's fourfold mission included studying biomedical effects of radiation, bone marrow injury by radiation, metabolism in bone and protein degradation; VA radioisotope work performed for clinical diagnosis and therapy and for research Links: AEC/ERDA/DOE, VA, NASA, HHS, DOD, Los Alamos, Oak Ridge (ORINS), School of Aviation Medicine Experiments or other radiation research: * Atomic Energy Project (of medical school) established in 1947 in conjunction with AEC and research is still ongoing; obtained broad AEC radioisotope license in early years; performed some classified research * nature of experiments: VA work included metabolism, blood volume, tissue clearance and muscular dystrophy studies; Total body irradiation; likely others include UCLA biomedical work connected to fallout/ weapons testing (Nevada Test Site), strontium/bones, blood studies * number of experiments unknown * period of study: medical school established in 1947; VA central advisory body established in 1947; local VA radioisotope unit, created in 1948, awarded general AEC license for radioisotopes in 1965; NASA connection beginning in 1961 Secret or classified research: Yes; aside from retrospective and other field work at bomb test sites, nature and extent of this work not yet explored AVAILABLE DATA Experiments: * Histories of research program: none specifically identified * "Start/stop" documents for specific experiments/programs: some protocols identified * Publications or reports for specific experiments/programs : articles on VA research; other reports (some classified) Program: * Record of chains of command for program decisions and review : objectives of Atomic Energy Project set out in reports; some information on VA chain of command set out in reports and correspondence * Funding source: AEC funding known, but documents not yet located 1 Was there secret or classified funding? Yes, but details not yet established Consent: What was the extant consent policy? Unknown how obtained; believe VA policy was to require only oral consent until early 1960's, no UC university program identified until 1960's * The institutional form for the policy: Not yet identified * Records of implementation: mechanism for recording consent unknown Subject selection: process unknown, but VA subjects would be a controlled population; 1965 VA 40-year age limit for volunteers (based on AEC model) Oversight: probably some from AEC/VA headquarters offices; minutes of VA Medical Center radioisotope committee meetings show local procedures; questions raised regarding lack of appropriate oversight of one VA project 2