Attachment 7 OVERVIEW Type of institution: university medical school; AEC national laboratory Mission: ANL designed as multi-disciplinary, nuclear research site; ANL established by AEC in 1946 as outgrowth of Metallurgical Project Links: AEC, VA, DOD, School of Aviation Medicine Key players: Robert Stone, J.J. Nickson, Willard Libby, Austin Brues, G.V. LeRoy Experiments or other radiation research: * AEC gave ANL a broad radioisotope license in early years, while it gave the University of Chicago authority to use such radioisotopes "as arranged with" ANL for "research and development" * site of plutonium injections as part of Manhattan Engineer District * classified research at Libby's Chicago lab as part of Operation Sunshine * nature of other experiments: Stone and Nickson did Total Body Irradiation; terminal patients given arsenic, calcium, strontium (bone studies); ANL was a main site of radium studies; thorium and carbon retention, iron distribution and cerium inhalation studies; VA/Northwestern/ANL study of tritiated thymidine; VA's LeRoy and Herta Spencer performed fallout/biodistribution studies with cesium and strontium; Chicago's toxicity lab did studies (unclear if human experiments ) for Army Chemical Corps during and after World War II; USAF Radiation lab (unclear if human experiments) at Chicago Secret or classified research: Yes, but details not fully explored AVAILABLE DATA Experiments: * Histories of research program: Yes, but fragmented on these issues and incomplete * "Start/stop" documents for specific experiments/programs: Reportedly compiled by ANL but none retrieved except as byproduct of Markey review * Publications or reports for specific experiments/programs : some Program: * Record of chains of command for program decisions and review : some, but not yet fully retrieved * Funding source: AEC, others expected but unknown Was there secret or classified funding? Yes, but nature and extent not yet identified Consent: What was the extant consent policy? unknown how obtained; mechanisms for institutionalizing and recording consent unknown * The institutional form for the policy: not known * Records of implementation: not identified 1 Subject selection: Terminal patients in several studies; retrospective study of people irradiated as fetuses; follow-up radium study at state hospital; Chicago technetium -99m study of pregnant women OVERSIGHT probably some from AEC headquarters; probably some university review UNIVERSITY OF CHICAGO/ARGONNE NATIONALLABORATORY (ANL)OVERVIEWType of institution: university medical school; AEC national laboratoryMission: ANL designed as multi-disciplinary, nuclear research site 2