DISCLAIMER The following is a staff memorandum or other working document prepared for the members of the Advisory Committee on Human Radiation Experiments. It should not be construed as representing the final conclusions of fact or interpretation of the issues. All staff memoranda are subject to revision based on further information and analysis. For conclusions and recommendations of the Advisory Committee, readers are advised to consult the Final Report to be published in 1995. TAB J þþþDRAFT þ FOR DISCUSSION PURPOSES ONLYþþþ MEMORANDUM TO: Members of the Advisory Committee on Human Radiation Experiments FROM: Advisory Committee Staff DATE: November 8, 1994 RE: Background Materials on Mid-Century HHS Radiation Research Activities The Department of Health and Human Services (HHS) is, and has been, the primary "civilian" sponsor of biomedical research. In prior briefing books we noted that, following World War II the National Institutes of Health (NIH) inherited many of the research contracts of the Committee on Medical Research, the coordinator of World War II medical research. In the 1949-52 period, representatives of the NIHand Public Health Service (PHS) participated in the DOD Joint Panel on the Medical Aspects of Atomic Warfare, at which human experimentation was debated and planned. In the ethics update section of this briefing book (Tab L) we note that the Atomic Energy Commission's (AEC's) Division of Biology and Medicine expressed some sentiment that military-related human experimentation be sponsored by HHS' predecessors. This tab provides documents that begin to give an overview of the mid-century radiological health and research efforts of HHS' predecessors, and the relation of this radiation research to Cold War military efforts. The documents, which were obtained from HHS and from the National Archives, include: Attachment 1: A July 21, 1950 letter from President Truman to the Administrator of the Federal Security Agency (FSA, HHS's mid-century predecessor) The President asked the Administrator to reexamine FSA programs, and "give first priority to those activities which contribute directly to national defense, including requests of other agencies for assistance." Attachment 2: An August 24, 1950 Memorandum from Dr. Dyer, Director of NIH, to the Directors of the NIH Institutes Dr. Dyer's memorandum attaches a memorandum to President Truman on the "need for support of medical research in defense plans." Attachment 3: Excerpts from a March 14, 1952 report on "Defense Activities of the Federal Security Agency" The report notes that "[b]oth the Atomic Energy Commission and the Department of Defense have called on the Public Health Service to use its research staff and to enlist the help of universities and medical schools in the study of radiation problems. These studies aim to determine precisely how ionizing radiation damages the body, and how much radiation human beings can stand in one dose or repeated doses and still be able to fight." Attachment 4: A May 13, 1952 report on "Defense Activity of the National Institutes of Health" (1950-1952) The section on "Radiation Research" (pages 30-31) notes, among other things: "A second major activity of the NIH relating to radiation research has been participation in the medical and biological aspects of atomic bomb tests. A large share of the expense of this activity has been borne by the Armed Forces Special Weapons Project. The substance of this work is classified." The extent to which HHS' predecessors participated in human experimentation and datagathering related to bomb tests remains to be more fully recovered. Attachment 5: Excerpts from a collection of materials, apparently prepared by PHS in about 1954, which outline the history and nature of HHS radiation-related programs The materials include, among other things: ù 5-1: A summary history of Radiation Health activities in the period 1945-52; ù 5-2: A summary of the 1953-54 Radiological Health programs; The section on "Military Applications" notes that: "The Atomic Energy Commission is on public record that the fall-out from tests, to date, has not resulted in significant health exposures. This belief is not fully concurred in by others who question the measurement and evaluation methods used by the Commission to study fall-out. Within the Commission and its contractor group, there are differences of opinion at the technical level." ù 5-3: A March, 1947 document entitled "Joint Statement of Public Health Service Personnel who had Experience with Crossroads," which summarizes the experience of PHS staff who served at the first peacetime atomic bomb tests; ù 5-4: A March 1947 document entitled "A Plan for Radiological Health Activities"; ù 5-5: An October 14, 1947 listing of radiation-related committee memberships; ù 5-6: 1949 documents relating to a Memorandum of Understanding between the AEC and the PHS regarding the roles to be played by the agencies in matters relating to ionizing radiation; ù 5-7: 1950 documents relating to environmental radiation research to be conducted by the PHS with the AEC at Oak Ridge, Savannah River, and Hanford; ù 5-8: A December 10, 1951 letter in which Shields Warren, head of the AEC's Division of Biology and Medicine, invites the Surgeon General, PHS, to appoint a member to an interagency committee to plan the biomedical components of atomic tests; ù 5-9: A 1952 document recording the "Findings and Recommendations from the First Meeting of a Group to Consider Radiobiological Activities in the Public Health Service"; and ù 5-10: A 1952 document entitled "Notes on P.H.S. Interagency Relationships in the Field of Radiobiology" which summarizes relationships with, among others, DOD and AEC entities. Attachment 6: A July 5, 1952 document entitled "Highlights of Public Health Service Activities in Radiological Health since the JCAE [Joint Committee on Atomic Energy] Fallout Hearings, May 4-8, 1949" Attachments Attachment 1 A July 21, 1950 Letter from President Truman to the Administrator of the Federal Security Agency Attachment 2 An August 24, 1950 Memorandum from Dr. Dyer, Director of NIH, to the Directors of the NIH Institutes Attachment 3 Excerpts from a March 14, 1952 Report on "Defense Activities of the Federal Security Agency." Attachment 4 A May 13, 1952 Report on "Defense Activity of the National Institutes of Health" Attachment 5 Excerpts From a Collection of PHS Materials Attachment 6 A July 5, 1952 Document Entitled "Highlights of Public Health Service Activities in Radiological Health since the JCAE Fallout Hearings, May 4-8, 1959."