Attachment 5

Project Specifications for "A Study of Intellectual 
Perceptual and Psychomotor Abilities of Patients following 
Radio-Therapy, "for the Air Force School of Aviation 
Medicine by the M. D. Anderson Cancer Center.









                      PROJECT SPECIFICATIONS


Project Title:    "A Study of Intellectual, Perceptual and         
Psychomotor Abilities of Patients following     Radio-Therapy."

a.   Requirement and Justification

    It is desired to measure certain mental and psychomotor abilities 
of patients who are undergoing radiation therapy in order to evaluate 
any differences in performance that may result from radiation effects.  
This information is urgently required by the 
U. S. Air Force in connection with the NEPA Project.  It is clear that 
before attempting to operate its proposed nuclear power aircraft, the 
U. S. Air Force must evaluate its radiation hazards.  There are no 
scientific data with which to assess these dangers of the EEPA 
aircraft in terms of their probable effects upon crew performance and 
well-being.  The most direct approach to this information would be by 
human experiments in specifically designed radiation studies) however, 
for several important resons this has been forbidden by to military 
authority.  Since the need is pres-sing, it would appear mandatory to 
take advantage of investigation opportunities that exist in certain 
radiology center by conducting special examinations and measures of 
patients who are undergoing radiation treatment for disease.  While 
the flexibility of experimental design in a radiological clinic will 
necessarily be limited, the information that may be gained from 
studies of patients is considered potentially invaluable) furthermore, 
this is currently the sole source of human data.

b.   Objective

     To determine the effects of exposures to ionizing radiations upon 
one's ability to peform simiple and complex mental and psycho-motor 
tasks in order to predict the effects upon the crew of opera-ting the 
EXPA aircraft.

c.   Project Plans

     The University of Texas, M. D. Anderson Hospital for Cancer 
Research, will make available to the School of Aviation Medicine Test 
Group selected patients who are scheduled for radiation therapy for 
various diseases.  Foillowing initial tests of the patients, the 
Hospital will administer the appropriate radiation treatment and will 
again submit the patient for testing.  Motiva-tion of the patients 
will be initially accomplished by the hospital staff.  The medical 
evaluation of the patients for purposes of the project will be done by 
especially employed personnel.  The mental and psychomotor testing 
will be done by the School of Aviation Medicine personnel as will the 
recording and evaluation of test data.



                              BUDGET

      Coordinating Medical Officer                   $3600.00

     Physicist                                       2000.00

     Secretary                                       2700.00

     Social Worker                                   1500.00

     Nurse, technician                               2000.00

     Technician, Clin-Path                           1500.00

     Patient hospital housing                        8750.00

     Outside housing                                 1000.00

     Miscellaneous (Drugs, Special diets, etc.)      5000.00

     Consultants:

        Physicist
        Therapist
        Internist                                    3000.00

                                                                   
                                      Total       $26,550.00


           The USAF School of Aviation Medicine Research Council   
desires that the Coordinating Medical Officer by a civilian 
M.D., preferably a fellow in internal medicine or radiology, or a 
second or third year resident in radiology or  internal medicine.

           The USAF School of Aviation Medicine desires further    
that the necessity of two Physicists be determined.  The above 
stated budget lists a physicist as the second item of   the budget and 
another physicist under "Consultants."



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