Attachment 6 Minutes from the Air Force Research Council Meeting held on January 14, 1954. MINUTES, RESEARCH COUNCIL MEETING, 14 January 1954 (cond't) 5. Major Schilling next presented a proposal from Dr. Eiseman of the University of Colordo, entitled, "Improvement of Coronary Artery Blood flow During Air Emboli Obstruction by Surface Tension Lowering Agents", at a cost of $3,505.00 for a period of one year. Major Schilling stated that Dr. Eiseman is a surgeon and personally known to him. He stated that the problem of air embolism is as important to the thoracic surgeon as it is to the Air Force. Dr. Eiseman proposes to add an emulsifying agent to the blood in the hopes of reducing the size of the bubbles in cases of air embolism. This has never been tried before and this work is starting from "scratch". Major Schilling stated that it was theoretically possible that the use of an emulsifying agent may lead to a method of treatment of air embolism. It was pointed out that the costs involved were extremely moderate. Dr. Clark stated that he felt that anyone who could set up such a concise experiment as outlined in the proposal must be a capable and serious investigator. Colonel McGraw moved that we recommend approval of the proposal but to removethe words "grant-in-aid". It was seconded by Dr. Clark. The vote to recommend approval was as follows: Colonel McGraw Yes Colonel Sweeney Yes Colonel Olson Yes Colonel Fischer Yes Major Payne Yes Dr. Clark Yes Mr. Rubenstein Yes 6. Lt Colonel Pickering, Major Thomas, and Captain Wald next presented a proposal from the M. D. Anderson Hospital, entitled "A Study of Intellectual Perceptual, Psychomotor, and Biomedical Status of Patients Following Exposures to Moderate Quantities of Ionizing Radiation", at a cost of $45,672.00 for a period of one year. It was pointed out that this is an extension of a contract but Mr. Pfister had raised the question as to whether a new contract or an extension would be written and an answer to that question would be determined upon his return from Hq. ARDC, Baltimore, Maryland. In any event, the work to be accomplished is a logical continuation of the work already being done at the M. D. Anderson Hospital under the present contract. Captain Wald stated that this project has been going on for 2 1/2 years. The subjects studied are patients of the M. D. Anderson Hospital who are receiving radiation therapy. He stated that we study the patients incidental to that therapy. He stressed the point that the patients studied cannot be considered as normal people. The first study accomplished under the contract involved those patients who had received repetitive small doses of radiation. This study was unproductive. Studies were then made on patients who received single large doses of total body radiation. The present study MINUTES, RESEARCH COUNCIL MEETING, 14 January 1954 (cond't) involves a study of a 15-day follow-up of patients who have received single large doses of total body radiation. The present study is beginning to show results, and a way is indicated for the development of a method of biological dosimetry. If these experi-ments are successful, it may be possible to determine the amount and intensity of radiation an individual received by studying a small sample of his blood. Colonel Pickering pointed out that in a nuclear powered aircraft, where shielding will be at a minimum there are questions of how long a flight and how many flights an individual may take in the course of his career and not be injured by the effects of nuclear power plant. He stated that this is the "best looking" biological test to date. Colonel Olson stated that the test is "after-the-fact" and how does it differ from the film badge test. Colonel Pickering stated that this method will deter-mine radiation exposure, quantitatively and qualitatively. The film badge test does not differentiate between the various types of radiation while this test may. Colonel McGraw then asked are the changes noted in the blood using this test the result of anything other than the effects of radiation. Captain Wald answered that wherein the patients were not normal people the changes could very well be the effect of the radiation on the abnormal tissue. Colonel McGraw then pointed out that in a GI series an individual received about 40 R's. He asked why couldn't we use them as con-trols. Captain Wald stated that he believed it was too early in the program to go into that but, of course, it was entirely pos-sible. Colonel McGraw then raised the question as to why we pay for the hospital care of patients. Captain Wald answered that these patients are out-patients and to retain them in the hospital in order to do our tests we must pay for their maintenance. Moreover, the patients that we want have to be capable of doing certain psychological tests, and therefore, we get these patients who are normally out-patients. Colonel McGraw stated that he thought that the cases studied were terminal cases. He was answered in the negative. Colonel McGraw then asked that if they are out-patients, why don't we put them in the out-patient "boarding house" at a cost of $7.00 per day rather than pay $17.00 a day to maintain them in the hospital. It was pointed out that there is some racial problem involved with colored patients and the colored out-patient maintenance facilities were located in another part of the city and, therefore, it would be difficult to have them transported back and forth to the hospital for testing. Colonel McGraw then asked about the cost of a bus driver and Captain Wald answered that the cost is for the driver on Saturday and Sunday when we do testing. On other days the State pays for this. The transportation is necessary because new annexes to the Anderson Hospital have been built, necessitating the movement of patients. Colonel McGraw stated that if we are paying for the maintenance of indigent of the State of Texas with research funds, and the State is also paying for the maintenance of those patients, there could be some difficulty. At this point it was not clear as to the costs involved in the maintenance of patients in the hospital as against a "boarding house" maintenance and it was suggested that this MINUTES, RESEARCH COUNCIL MEETING, 14 January 1954 (cond't) matter become a part of the negotiations of the Contracting Officer. Captain Wald then discussed the techniques of his new tests used in the experiments for bilogical dosimetry. Colonel McGraw asked will we be able to continue this work after Captain Wald and Captain Rambach are discharged. Captain Wald stated that Dr. Booth of the M. D. Anderson Hospital staff, who is just recent-ly coming into the project, will be completely briefed on the work to date. Dr. Clark moved that we recommend approval of the propo-sal, but that the costs of maintenance of the patient on an "in-hospital" or "out-hospital" basis be subject to negotiation. It was seconded by Major Payne. The vote to recommend approval was as follows: Colonel McGraw Yes Colonel Sweeney Yes Colonel Olson Yes Colonel Fischer Yes Major Payne Yes Dr. Clark Yes Mr. Rubenstein Yes The meeting adjourned at 1600 hours. SEYMOUR SCHWARTZ HENRY M. SWEENEY Major, USAF (MSC) Colonel, USAF Research Secretary Acting Director of Research APPROVED: EDWARD J. KENDRICKS 21 January 1954 Brigadier General, USAF (MC) (Date) Commandant DISTRIBUTION: 1 - Central Files 1 - Budget & Fiscal 1 - ARDC Sub-PROCUREMENT 1 - Research Secretary 1 - Purchasing & Contracting