Attachment 2



                          WAR DEPARTMENT
                        CORPS OF ENGINEERS
                  OFFICE OF THE DISTRICT ENGINEER
                        MANHATTAN DISTRICT
                       OAK RIDGE, TENNESSEE

                                                24 December 1946.



Subject:  Administration of Radioactive Substances to Human
          Subjects.

To:       The Area Engineer, California Area, Berkeley,
          California.

     1.   Reference is made to Progress Report P-770 under
contract number W-7405-Eng-48-A, dated 26 November 1946 from the
Berkeley Area.

     2.   The first paragraph of this report indicates that
certain radioactive substances are being prepared for intravenous
administration to human subjects as a part of the work of the
contract.  After discussion with Colonel James P. Cooney, Medical
Director, Manhattan Project, it is felt that such work does not
come under the scope of the Manhattan District Program and should
not be made a part of its research plan.

     3.   It is therefore deemed advisable by this office not
only to recommend against work on human subjects but also to deny
authority for such work under the terms of the Manhattan
contract.  You will take immediate action to stop this work under
this contract, and report to this office upon compliance.

                                   K. D. NICHOLS,
                              Colonels, Corps of Engineers,
                                   District Engineer.


Repository  Oak Ridge Opr.
	    Records Hlding Task Group
Collection  Class, Doc. 1944-94

Box No.     161 82,540 Bldg. 2714-H Vault

Folder     

	   	     UNCLASSIFICATION RECOMMENDED

			Sgd. R.B. Burdett, Analysas
		      Name (ADD) - Organization

		      Date:  7/27/94


		     DECLASSIFICATION AUTHORIZED

			MALCOLM THEISEN, ANALYSAS
		      Name (ADD) - Organization


		     Date  7-29-94